1. Infertility: Male Factor

1. A cross‑sectional study of semen oxidative stress parameters and sperm DNA fragmentation in infertile men attending a tertiary centre in India
2. A comparative study of seminal plasma zinc levels in men with primary versus secondary infertility
3. A prospective observational study of testicular volumetry (ultrasound) and hormonal profiles in non‑obstructive azoospermia patients
4. A comparative study of outcomes of microsurgical varicocelectomy versus non‑microsurgical approach in sub‑fertile men with varicocele
5. An analytical cross‑sectional study of lifestyle (smoking, BMI, alcohol) correlates of sperm motility in Indian urban male infertile population
6. A comparative observational study of ICSI outcomes in men with high sperm DNA fragmentation versus low fragmentation
7. A prospective observational study of endocrine (FSH/LH/testosterone) and metabolic (insulin resistance) parameters in male infertility in India
8. A cross‑sectional study of the prevalence of Y‑chromosome microdeletions among azoospermic men in an Indian tertiary hospital
9. A comparative study of therapeutic efficacy of antioxidant therapy versus standard treatment on sperm parameters in oligoasthenoteratozoospermia

• A cross‑sectional study on psychosocial impact and sexual dysfunction prevalence in male partners of infertile couples in India

2. Infertility: Female Factor

1. A cross‑sectional study of ovarian reserve markers (AMH, antral follicle count) and reproductive outcomes in Indian women with unexplained infertility
2. A comparative study of tubal patency assessment via HSG versus laparoscopy in infertile women
3. A prospective observational study of endometrial receptivity (ultrasound Doppler + histology) and IVF success in Indian women
4. A comparative study of laparoscopic surgery versus expectant management in endometriosis‑related infertility
5. A cross‑sectional study of uterine fibroids’ size, location and impact on ART outcomes in Indian women
6. A comparative observational study of lifestyle factors (BMI, PCOS, thyroid) on fertility outcomes in women pursuing ART
7. A prospective observational study of premature ovarian insufficiency (POI) prevalence and outcomes in Indian women
8. A comparative study of intra‑uterine insemination (IUI) success rates in women with minimal/mild endometriosis versus no endometriosis
9. A cross‑sectional study on ovarian hyperstimulation syndrome risk factors in Indian IVF patients

• A comparative observational study of natural cycle IVF versus stimulated cycle IVF in poor‑responder Indian women

3. Assisted Reproductive Technology (ART)

1. A cross‑sectional study of embryo grading (day 3 versus day 5) and implantation rates in Indian IVF cycles
2. A comparative study of fresh versus frozen embryo transfer outcomes in Indian ART practice
3. A prospective observational study of luteal phase support regimens (vaginal progesterone versus oral) and pregnancy outcomes in IVF cycles
4. A comparative study of IVF outcomes in women with PCOS using GnRH antagonist versus long‑GnRH agonist protocol
5. A cross‑sectional study of cumulative live birth rates in Indian ART centre over five years
6. A comparative observational study of intracytoplasmic sperm injection (ICSI) versus conventional IVF in male factor infertility in India
7. A prospective observational study on cryopreservation of oocytes: survival rates and subsequent fertilisation in Indian women
8. A comparative observational study of time‑lapse embryo monitoring versus standard embryo culture in IVF outcomes
9. A cross‑sectional study of cost‑effectiveness of low‑cost ART protocols in Indian tertiary centre

• A comparative study of obstetric and perinatal outcomes in singleton pregnancies resulting from ART versus spontaneous conception in Indian cohort

4. Reproductive Endocrinology & Metabolic Factors

1. A cross‑sectional study of insulin resistance and AMH levels in Indian women with PCOS undergoing fertility treatment
2. A comparative study of thyroid dysfunction impact on ART outcomes in Indian women
3. A prospective observational study of obesity and reproductive hormone changes in infertile Indian women
4. A cross‑sectional study of metabolic syndrome prevalence in men undergoing evaluation for infertility in India
5. A comparative observational study of women with PCOS and without PCOS undergoing IUI: fertility outcomes and complications
6. A prospective study of vitamin D deficiency status and its correlation with reproductive outcomes in Indian infertile couples
7. A cross‑sectional study of adrenal androgen levels and ovarian response in women undergoing IVF in India
8. A comparative study of ovulation induction protocols in anovulatory infertility: clomiphene versus letrozole in Indian women
9. A prospective observational study of the effect of lifestyle intervention (diet + exercise) on metabolic and fertility outcomes in obese infertile Indian women

• A cross‑sectional study of serum anti‑Müllerian hormone and inhibin B levels in Indian women with diminished ovarian reserve

5. Reproductive Surgery & Endoscopic Management

1. A comparative study of laparoscopy versus laparotomy for tubal‑factor infertility in Indian women: fertility outcomes and complications
2. A cross‑sectional study of hysteroscopic evaluation and correction of uterine septum in recurrent pregnancy loss patients in India
3. A prospective observational study of myomectomy (open versus laparoscopic) and subsequent fertility outcomes in Indian women
4. A comparative observational study of surgical versus expectant treatment of hydrosalpinx prior to IVF in Indian setting
5. A cross‑sectional study of pelvic adhesions grading and reproductive outcome in women with infertility undergoing laparoscopy
6. A comparative study of robotic‑assisted versus standard laparoscopy in endometriosis surgery for infertility in Indian tertiary centre
7. A prospective observational study of tubal recanalisation outcomes (laparoscopic microsurgery) in Indian women with sterilisation reversal
8. A cross‑sectional study of ovarian drilling (laparoscopic) outcomes in Indian women with PCOS and infertility
9. A comparative observational study of intraoperative anti‑adhesion barrier versus no barrier in reproductive outcome post‑surgery in Indian women

• A cross‑sectional study of postoperative ovarian reserve changes (AMH) after conservative ovarian surgery for endometrioma in Indian women

6. Reproductive Genetics & Embryology

1. A cross‑sectional study of chromosomal abnormalities in couples with recurrent implantation failure undergoing ART in India
2. A comparative study of pre‑implantation genetic testing (PGT) versus no PGT in IVF outcomes in Indian couples with recurrent miscarriage
3. A prospective observational study of mitochondrial DNA copy number in oocytes and subsequent embryo development in Indian IVF cycles
4. A cross‑sectional study of single‑nucleotide polymorphisms (SNPs) in infertility‑related genes in Indian infertile population
5. A comparative observational study of embryo aneuploidy rates in older versus younger Indian women undergoing IVF
6. A cross‑sectional study of sperm telomere length and reproductive outcomes in Indian men with unexplained infertility
7. A prospective observational study of epigenetic marks (methylation) in embryos from ART and correlation with neonatal outcomes in Indian cohort
8. A comparative study of blastocyst‑stage versus cleavage‑stage biopsy for PGT and subsequent live birth rates in Indian IVF programme
9. A cross‑sectional study of zona pellucida thickness measurement and its relation to fertilisation rates in Indian IVF cycles

• A comparative observational study of intracytoplasmic morphologically selected sperm injection (IMSI) versus conventional ICSI in Indian male infertility cases

7. Obstetric Outcomes & Maternal‑Fetal Implications of Reproductive Interventions

1. A cross‑sectional study of maternal and perinatal outcomes in pregnancies conceived via ART in an Indian tertiary hospital
2. A comparative observational study of obstetric complications (placenta previa, pre‑eclampsia) in singleton versus twin pregnancies after ART in India
3. A prospective observational study of fetal growth patterns and birth weight in women with fertility treatment versus spontaneous conception in India
4. A comparative study of caesarean section rates and indications in women with prior ART conception versus spontaneous conception in India
5. A cross‑sectional study of neonatal outcomes (NICU admission, prematurity) in ART‑conceived infants in India
6. A comparative observational study of placental pathology in pregnancies following ART versus natural conception in Indian context
7. A prospective observational study of long‑term developmental outcomes (2 year) in children born following ART in India
8. A cross‑sectional study of mode of delivery choices in women with prior varicocelectomy/infertility treatment in India
9. A comparative study of psychological stress and postpartum depression rates in mothers after ART versus natural conception in India

• A prospective observational study of incidence of hypertensive disorders in pregnancy in women who had fertility treatments in India

8. Contraception, Family Planning & Reproductive Health in Infertility Settings

1. A cross‑sectional study of knowledge, attitudes and practices of contraception among infertile couples attending a reproductive medicine clinic in India
2. A comparative study of uptake of long‑acting reversible contraception (LARC) after infertility treatment in urban versus rural Indian settings
3. A prospective observational study of return to fertility after various contraceptive methods in Indian women seeking fertility preservation
4. A cross‑sectional study of unmet need for contraception among women with infertility issues in India
5. A comparative observational study of male partners’ involvement in family planning decisions in couples with infertility versus fertile couples in India
6. A cross‑sectional study of barriers to accessing infertility care and assisted reproduction in low‑income Indian women and its relation to family planning practices
7. A prospective observational study of outcomes of fertility preservation counselling in women undergoing pelvic surgery for benign conditions in India
8. A comparative study of awareness and acceptance of sperm/ovarian cryopreservation in young Indian cancer patients prior to gonadotoxic therapy
9. A cross‑sectional study of provider practices and compliance with national guidelines for ART and fertility services in India

• A comparative observational study of contraceptive failure rates in women who previously underwent fertility treatment versus those who did not in India

9. Psychosocial, Ethical and Economic Aspects of Reproductive Medicine

1. A cross‑sectional study of quality‑of‑life, anxiety and depression in couples undergoing ART in India
2. A comparative study of treatment cost burden and out‑of‑pocket expenditure in public versus private fertility clinics in India
3. A prospective observational study of ethical decision‑making and consent practices in donor gamete IVF in India
4. A cross‑sectional study of societal and cultural perceptions of infertility and its treatment among Indian rural and urban populations
5. A comparative study of male and female partners’ coping mechanisms in couples with infertility in India
6. A cross‑sectional study of stigma and marital adjustment in Indian couples waiting for fertility treatment
7. A prospective observational study of registry‑based data on live‑birth outcomes and long‑term follow‑up cost‑effectiveness of ART in India
8. A comparative observational study of assisted reproductive service utilisation across socioeconomic strata in India
9. A cross‑sectional study of knowledge and attitudes of healthcare providers about fertility preservation in India

• A comparative study of regulation, accreditation and outcome transparency practices among ART clinics in India

10. Recent Studies and Emerging Trends in Reproductive Medicine

1. A cross‑sectional observational study of embryo morphokinetics using time‑lapse technology and correlation with implantation in an Indian IVF centre
2. A comparative study of vitrified oocyte survival and live birth rates using different cryoprotectant protocols in India
3. A prospective observational study of artificial intelligence (AI) in embryo selection and its correlation with outcomes in Indian IVF cycles
4. A cross‑sectional study of fertility preservation uptake and outcomes in cancer survivors in India
5. A comparative study of non‑invasive embryo assessment (spent media metabolomics) versus conventional embryo assessment in Indian IVF practice
6. A prospective observational study of wearable fertility monitoring devices and their accuracy compared to standard methods in Indian women
7. A cross‑sectional study of sperm and seminal vesicle microbiome and its relation to male infertility in India
8. A comparative observational study of novel adjuvant therapies (e.g., platelet‑rich plasma ovarian rejuvenation) versus standard management in poor‑responder Indian women
9. A prospective observational study of outcomes of on‑site versus off‑site embryo culture incubators (lab infrastructure variation) in Indian ART centres

• A cross‑sectional study of epigenetic profiling (DNA methylation) of cord blood in babies born after ART versus natural conception in India